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Understanding Cannabinoids: CBN vs CBD

While there are many cannabinoids that may enhance the therapeutic effects of hemp products, the most common renowned product is the phytochemicals in the Cannabis genus that contain the tetrahydrocannabinol or THC. This is the substance that is responsible for all of the psychoactive effects of cannabis. CBD has long been associated with the variety that offers up the best help benefits without offering up the high that the THC gives to users.

While the CBD may not be the feature that is in all of the hemp products, it’s a by-product of the THC. Hemp Genix, Wholesale CBD Oil in Springdale, has 80% purity compared to competitors at 17%-40%.  The CBN doesn’t bind to the body’s cannabinoid receptors like the THC does. It’s long been known to give a stronger sedative effect when it’s used in combination with the THC.

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At Hemp Genix, all of our products are made with 100 percent USA, Zero THC and 80 percent purity Wholesale full-spectrum CBD oil in Springdale. This is carefully derived from a variety of cultivars of hemp which contain an abundance of cannabinoids.

A lot of people are very familiar with CBD or Cannabidiol. This is found in highly concentrated amounts in a variety of products. However, there are lots of cannabinoids that are found in hemp. These have shown a variety of benefits in studies. All of our products offer you full-spectrum hemp oil. This also includes all of our cannabinoids that are found in the plant. We don’t want you to miss out on any of the benefits.

 

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This is the most abundant cannabinoid in the hemp oil. It makes up 90 percent of the content of cannabinoid. It’s non-psychoactive and the focus is on how it benefits the body via the hemp oil. It has minimal affinity for CB1 or CB2 receptors. The main focus on interaction is in the endocannabinoid system and it acts as an indirect antagonist toward the cannabinoid antagonists. This, in turn, may allow the CBD to temper the high that is caused through the THC. Wholesale CBD Oil in Springdale from Hemp Genix are over 80 percent pure and CBD makes up the majority of the Oils weight. Industry averages and nearly all of the other products with cannabinoids and brands average in at 17 to 40 percent purity.

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What’s The Difference Between CBD And CBN?

Cannabis has a number of cannabinoids in which the most abundant are the levels of THC. There are 9 tetrahydrocannabinol as well as CBD and CBN. This is the active ingredient that makes you high. The THC is in the plant and the CBD is the precursor and the CBN is the metabolite of the THC. As the cannabis ages, the THC level breaks down into the CBN.

 

This also leads researchers to believe that the CBD might give some protection against ecstasy-derived neurotoxins or long-term depletion of the serotonergic receptions. While this is still speculation, it’s investigating further. The CBD is usually present in significant enough quantities in such products as hashish or cannabis resins. However,r it’s also in the herbal cannabis referred to as skunk in smaller amounts.

Overall, the CBN is a great cannabinoid that offers up a varied range of therapeutic applications that work together with the rest of the “team” in order to offer up the best possible results. Clearly, more clinical trials are required to see how else it can benefit patients.

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Whoopi Goldberg, the actress and co-host of daytime talk show The View, is launching a new company to sell a centuries-old remedy for women's menstrual pain:  marijuana.

Based in San Francisco, Whoopi & Maya is positioned as a by-women, for-women pot edibles business. Goldberg is teaming with  cannabis grower and edibles maker Maya Elisabeth, herbalist Alexis Gandara, and pot industry PR company founder Evan Nison on the venture, which will begin selling products in marijuana dispensaries in its home city in April.

"I see cannabis as a step in the direction of new forms of medicine, but it also has its place in history and goes back to Queen Victoria," Goldberg tells Inc. "There are many people trying to get you high. We're just trying to get you comfortable."

credit: Michael OsborneCREDIT: Timothy WhitMichael Osborne

The company's products, which are all infused with THC and medicinal herbs such as elderberry, red raspberry leaf, and Guelder-rose, include raw sipping cacao for hot chocolate, a bath salt soak, a body balm for use as a local anesthetic, and a tincture to add to liquids or drop under the tongue. All of the products were developed specifically to relieve menstrual discomfort.

Only a handful of dispensaries will sell Whoopi & Maya products at launch but the founders expect to expand to other stores and new regions over the course of the next year. It will sell non-psychoactive versions of its products made with CBD, a chemical in cannabis that helps reduce inflammation and acts as an anti-convulsant, in states without a legal marijuana market.

Goldberg says she was speaking to her daughter when she came up with the idea for a woman-focused edibles company last year. "We were trying to figure out a product [for menstrual pain] that wasn't full of ingredients with names we couldn't pronounce, and then it hit me." She says she had been using a vape pen with THC oil for her glaucoma, but the more research she did the more she read about THC topical rubs and tinctures.

The founders raised $650,000 from friends and family over the last year to launch the company. All of the pot comes from an all-female-run medical marijuana farm in northern California, which Elisabeth has been involved with since 2008. Goldberg says the company is open to expanding its market beyond solely women, especially as pot sales become legal in more states and the U.S. dispels what she calls "the lie of marijuana being a Schedule I drug" that's as harmful as harder substances such as heroin.

Eventually, Whoopi & Maya also could look to broaden its product lines to other medicinal applications. "Marijuana is like penicillin, Goldberg says. "The amount of things cannabis seems to help is like the amount of things penicillin seems to help." 

 

A Majority of American Voters Support Legalizing Marijuana

In a historic move, the U.S. Drug Enforcement Agency granted approval for a nonprofit to study marijuana's medical benefits on military veterans suffering from combat-related psychological disorders.

The Multidisciplinary Association for Psychedelic Studies (MAPS), a California-based nonprofit that studies medical uses of psychotropic drugs, will conduct the clinical trial, which will be a double-blind, placebo-controlled trial using the whole plant (not an extract or pill version). The trial is the first in U.S. history to receive full approval from the DEA and FDA.

The study will examine whether medical marijuana can treat Post-Traumatic Stress Disorder in 76 U.S. military veterans. The veterans have treatment-resistant PTSD and haven't found relief from other medications. The study will look into how different strains and doses of marijuana can benefit the veterans and look into potential side effects, a press release from MAPS says.

The trial intends to develop "smoked botanical marijuana into a legal prescription drug" approved by the FDA, MAPS says in a statement.

MAPS received a $2.16 million grant from Colorado's Department of Public Health and Environment (CDPHE) to conduct the trial.

"We have been working towards approval since we opened the Investigational New Drug Application (IND) with the FDA in 2010," said Amy Emerson, executive director and director of clinical research for the MAPS Public Benefit Corporation, in a release. "We are thrilled to see this study overcome the hurdles of approval so we can begin gathering the data. This study is a critical step in moving our botanical drug development program forward at the federal level to gather information on the dosing, risks, and benefits of smoked marijuana for PTSD symptoms."

MAPS, which was founded in 1986, has raised over $36 million for psychedelic therapy and research and education in marijuana's medical benefits.


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