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Understanding Cannabinoids: CBN vs CBD

While there are many cannabinoids that may enhance the therapeutic effects of hemp products, the most common renowned product is the phytochemicals in the Cannabis genus that contain the tetrahydrocannabinol or THC. This is the substance that is responsible for all of the psychoactive effects of cannabis. CBD has long been associated with the variety that offers up the best help benefits without offering up the high that the THC gives to users.

While the CBD may not be the feature that is in all of the hemp products, it’s a by-product of the THC. Hemp Genix, Wholesale CBD Oil in McBee, has 80% purity compared to competitors at 17%-40%.  The CBN doesn’t bind to the body’s cannabinoid receptors like the THC does. It’s long been known to give a stronger sedative effect when it’s used in combination with the THC.

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At Hemp Genix, all of our products are made with 100 percent USA, Zero THC and 80 percent purity Wholesale full-spectrum CBD oil in McBee. This is carefully derived from a variety of cultivars of hemp which contain an abundance of cannabinoids.

A lot of people are very familiar with CBD or Cannabidiol. This is found in highly concentrated amounts in a variety of products. However, there are lots of cannabinoids that are found in hemp. These have shown a variety of benefits in studies. All of our products offer you full-spectrum hemp oil. This also includes all of our cannabinoids that are found in the plant. We don’t want you to miss out on any of the benefits.

 

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This is the most abundant cannabinoid in the hemp oil. It makes up 90 percent of the content of cannabinoid. It’s non-psychoactive and the focus is on how it benefits the body via the hemp oil. It has minimal affinity for CB1 or CB2 receptors. The main focus on interaction is in the endocannabinoid system and it acts as an indirect antagonist toward the cannabinoid antagonists. This, in turn, may allow the CBD to temper the high that is caused through the THC. Wholesale CBD Oil in McBee from Hemp Genix are over 80 percent pure and CBD makes up the majority of the Oils weight. Industry averages and nearly all of the other products with cannabinoids and brands average in at 17 to 40 percent purity.

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What’s The Difference Between CBD And CBN?

Cannabis has a number of cannabinoids in which the most abundant are the levels of THC. There are 9 tetrahydrocannabinol as well as CBD and CBN. This is the active ingredient that makes you high. The THC is in the plant and the CBD is the precursor and the CBN is the metabolite of the THC. As the cannabis ages, the THC level breaks down into the CBN.

 

This also leads researchers to believe that the CBD might give some protection against ecstasy-derived neurotoxins or long-term depletion of the serotonergic receptions. While this is still speculation, it’s investigating further. The CBD is usually present in significant enough quantities in such products as hashish or cannabis resins. However,r it’s also in the herbal cannabis referred to as skunk in smaller amounts.

Overall, the CBN is a great cannabinoid that offers up a varied range of therapeutic applications that work together with the rest of the “team” in order to offer up the best possible results. Clearly, more clinical trials are required to see how else it can benefit patients.

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Ten Uses for CBD Oil

CBD oil is an oil that is known to have some powerful medicinal properties. It is harvested from cannabis, and it is particularly special because while it has medicinal properties, it does not have the psychoactive effect of THC.

CBD oil has a lot of uses, but here are ten particularly interesting ones.

1 - Improving recovery time for athletes

CBD can help to reduce pain and inflammation, promote healing of injuries, and improve the general post-exercise recovery time for athletes by preventing muscle soreness.

2 - Combating nicotine addiction.

Smokers who are addicted to nicotine could benefit from inhaling CBD. While CBD does not contain nicotine, it does help to reduce withdrawal symptoms, making it easier to cut down on the amount of nicotine that you take in. You will still, however, need to work to break the habit of smoking.

3 - Clearer skin

CBD can help to reduce skin inflammation and reduce the appearance of oily acne spots. It reduces the synthesis of lipids that cause the spots, thereby reducing the problem of clogged pores and giving you clearer looker, fresher and more vibrant skin, as well as an improved overall sense of wellbeing.

4 - Blood sugar regulation

While CBD won't help to combat Type 1 diabetes, it is thought that it could help to reduce the risk of Type 2 diabetes in adults. Certainly, it has been found to prevent mice from developing diabetes. It does this by preventing the production of IL-12. This cytokine is known to play a roll in several common auto-immune diseases, so researchers are paying a lot of attention to the effects of CBD on the immune system.

5 - Managing the Symptoms of Fibromyalgia

Fibromyalgia is a chronic and very serious condition. There are some promising studies out there which show that using cannabis can help to reduce the symptoms of fibromyalgia far more than more conventional painkillers can. CBD is one of the cannabinoids that is used in the treatment of inflammation based medical conditions, and this gives hope to people who are living in areas where medical marijuana is still frowned upon.

6 - Anxiety and Stress Disorders

People who suffer from anxiety, panic attacks and post traumatic stress disorder can benefit from CBD. While the cannabinoid is best known for its anti-inflammataory effects, it does actually have an anti-anxiety effect too. It is an anti-psychotic, and it has a balancing effect on the mind that is hugely beneficial to those who are struggling with anxiety.

7 - Insomnia

One of the most difficult things for someone who is stressed out is getting a good night's sleep, and that's another thing that CBD can help you with. Instead of taking pharmaceuticals that will leave you feeling groggy the following morning, why not try taking something that will leave you feeling fresher and more energized when you wake up?

8 - Anti-aging

CBD contains powerful anti-oxidants. These can help to prevent neurodegenerative disorders, and leave you feeling fitter and more healthy in general. They won't "wind back wrinkles", but they will give you a youthful vigor in other ways, and if you're less stressed and feeling better rested too, then that's going to show in every aspect of your life.

9 - Help for epileptics

The FDA recently approved a request to run trials on CBD as a method of managing epilepsy. Now, these trials are still very early on in the process, and CBD has not been approved as an anti-convulsant. It would be irresponsible to suggest that people stop taking their traditional medication in favor of CBD. However, it's something worth considering.

10 - A pick me up

If you're generally healthy, but just feeling a little run down, sore, tired or stressed, then CBD could well be the answer. It can be enjoyed in food, as an edible, or as a vape.

CBD is not legal in every part of the world. It is considered a drug in some countries. Before you buy some, make sure that you know what you are getting, and whether you are acting within the law in your country. Take care to make sure that you're buying true CBD oil as well, not just hemp oil.

The First Family of Legal Marijuana

Editor's note: This article is part of Inc.'s 2015 Best Industries report.

In the beginning, Pete Williams grew medical marijuana in his basement. He grew strains with names like White Widow and Sour Diesel, and it was good. Eventually, Pete's older brother Andy joined him and the business soon became too big for the basement. Five years later, Medicine Man is one of the largest and most successful cannabis dispensaries in the state of Colorado. With two retail locations, one in Denver and the other in Aurora, the company produced 7,000 pounds of pot and made $8 million in revenue in 2014. 

The Williams brothers--along with their sister, Sally Vander Veer, who helped with Medicine Man's launch and came on as CFO in 2013--are one of the many success stories in Colorado's $1.5 billion legal weed industry. According to a report by Convergex Group, the state's 300 licensed marijuana businesses generated $350 million in revenue in 2014, a figure that's expected to grow by 20 percent this year. 

Out of the basement.

In 2008, the recession crippled Pete's custom tile business. After 18 years of marriage, he and his wife got divorced, and he needed to make money to support his two children. A friend gave him 16 pot plants, each one small enough to fit inside a Dixie cup, and told him there's good money in "caregiving," or growing weed for medical patients. A born tinkerer, Pete built a complex grow system incorporating hydroponics and aeroponics techniques. That first year, he made $100,000 out of his basement selling to dispensaries.

President Obama declared state-legalized medical cannabis a "low priority" for law enforcement the following year. That's when Andy came down to the basement with a plan. "I'll be the businessman and you be the green thumb," Andy, now the president and chief executive of Medicine Man, remembers telling Pete.

With a loan of just over a half-million dollars from their mother, the brothers leased a 20,000-square-foot space in a warehouse in Denver's Montbello neighborhood and built a state-of-the-art hydroponics-based system. At that time, the brothers were selling wholesale, but in December 2010 a new law was enacted requiring cannabis growers to sell their product directly to customers. Andy and Pete built a dispensary in the front of the warehouse and ceased their wholesale business.  

By 2013 Medicine Man was able to buy the warehouse and had generated $4 million in revenue. But with the legalization of recreational marijuana on the horizon, Andy knew the company needed to raise more money to expand their grow facility and up production in preparation for a spate of new customers. He pitched cannabis angel investor network ArcView Group in California and secured $1.6 million in funding. 

"Andy was the right entrepreneur at the right time for an investment opportunity. At the end of the day, it's clear Andy thought all the way through the pieces of the puzzle," says ArcView CEO Troy Dayton. (Neither Dayton nor ArcView is a Medicine Man investor.) "In a nascent industry, companies get traction not only when they are early but when they are a great business and composed of great people--Andy has both." 

On January 1, 2014, the first day sales of recreational marijuana were officially legal, Medicine Man sold 15 pounds of pot and made close to $100,000. Meanwhile Pete, Andy, and Sally have been looking ahead to a day when cannabis becomes legal nationwide. To ensure another revenue stream, the trio created Medicine Man Technologies, a consulting firm that offers turnkey packages to entrepreneurs who want to start pot business. Medicine Man Technologies, which has helped clients build medical facilities in New York, Illinois, Florida, and Nevada, will become a publicly traded company on the over-the-counter market this summer.

The challenges of being a potpreneur. 

In spite of the safe haven Colorado has created, pot businesses still face at least two major hurdles: First, until major banks decide it's safe to bring on marijuana clients, the businesses must deal exclusively in cash. Medicine Man, which says it brought in $50,000 a day in December, has had to invest heavily in security measures. Its two locations are equipped with a total of more than 100 cameras trained inside and out, as well as bulletproof glass and doors. The company has also hired security company Blue Line Protection Group to supply armed guards for the dispensaries and warehouses, and armored trucks to run money from the safe to pay bills, the government, and vendors. 

Cannabusinesses also face extremely high taxes, in some cases exceeding 50 percent. But thanks to Pete's super-efficient grow operation, which produces a gram of marijuana for the comparatively low cost of $2.50, Medicine Man has been able to slash prices for the customer while staying profitable--so even after the state takes its cut, the company's margins are 30 to 40 percent, Sally says. 

Exit strategy.

It's easy to look at the Williamses, or watch them on MSNBC's reality show Pot Barons of Colorado, and believe they have the life. The trio seem to be sitting on top of the Mile High City's legal weed industry, but they didn't get up there without personal sacrifice. For example, Andy's decision to give up a stable job to launch Medicine Man cost him his marriage.  

"One thing people don't understand is that the entrepreneurs who started the industry in Denver are pioneers in the truest sense. What it takes to be a pioneer is vision, the ability to see something, and the courage to go after it despite the risks," he says. "The risks weren't just about money--they were about our reputations, our freedom, and our families. People risked everything for it."

After years of dealing with all those risks and sacrifices, the Williamses now say they're ready to put their feet up and enjoy the rewards of building the "Costco of marijuana." The siblings are currently in talks with private equity firms regarding an acquisition. They put the current value of the 80-employee business at $30 million, and say it will bring in $15 to $18 million in revenue in 2015.

"We began this whole thing with an end game in mind," Pete says. "We're all in our late 40s and we don't want to work for the rest of our lives." 

He adds that they're willing to sell their majority stake, but they'd like to hang on to 5 to 10 percent. "If we don't sell out, [an acquiring company] will buy our biggest competitor," he says. "If we hook up with the right people, Medicine Man can be a household name like Pepsi or Coke. [People will say,] 'Go get me a pack a Medicine Mans, honey.'"


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